Merck & Co Inc

MRK: XNYS (USA)

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Moderna and Merck: Intismeran's Positive Phase 3 Readout Confirms mRNA Potential in Oncology

Karen Andersen

Aug 19, 2026

In a Phase 3 study, individualized neoantigen therapy intismeran improved recurrence-free survival and distant metastasis-free survival in melanoma patients when combined with Keytruda, relative to Keytruda alone. Moderna shares rose nearly 150% and Merck rose over 10% intraday on Aug. 19.

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Merck & Co Inc

Moderna and Merck: Intismeran's Positive Phase 3 Readout Confirms mRNA Potential in Oncology

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