Dow Jones Top Company Headlines at 5 AM ET: Roche Breast-Cancer Treatment Falls Short of Primary Goal in Late-Stage Study | GSK ...

Roche Breast-Cancer Treatment Falls Short of Primary Goal in Late-Stage Study

The combination of Roche's investigational drug, giredestrant, with Pfizer's Ibrance didn't lead to a statistically significant improvement among patients with advanced breast cancer.

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GSK Sells Rights to Drug Candidate to Alfasigma for Up to $690 Million

Under the deal, Alfasigma will gain rights to develop, manufacture and commercialize linerixibat.

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Activist Starboard Takes Big Stake in French-Fry Maker Lamb Weston

Starboard Value is pushing the company to speed up improvements and cost cutting to boost its underperforming stock.

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AI Needs Management Consultants After All

OpenAI, Anthropic strike deals with consulting firms to spread artificial intelligence through the business world.

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Volkswagen Dealers Revolt Over Plan to Sell a New Brand of SUV Directly to Consumers

The latest of several lawsuits seeks to stop the automaker from bypassing dealerships.

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Kalshi and Polymarket Are Each Eyeing Roughly $20 Billion Valuations

The rival prediction markets have spoken with investors about roughly doubling their previous valuations.

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BlackRock Sticks to Redemption Minimum on Credit Fund, Sends Shares Lower

A BlackRock fund said it would not buy back more than 5% from investors. Facing a similar situation, rival Blackstone took the opposite stance.

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'Hoppers' Scores Pixar's Biggest Original Animated Opening in Years

The well-reviewed animated movie opened with $88 million worldwide this weekend., while "The Bride!" flopped.

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Paramount says its Warner Bros. deal can work without big layoffs. Hollywood isn't buying it.

Hollywood is bracing for big job cuts at Warner Bros. Discovery when its merger with Paramount closes, even as Paramount has insisted it can make the deal work without many layoffs.

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Costco, Sam's Club Spark China's Consumer Shift to Warehouse Shopping

As warehouse clubs and private labels surge, China's consumers are reshaping retail-and squeezing the pricing power of multinational brands.

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Salesforce Stock Might Not Be an AI Loser After All

AI agents like Claude Cowork have terrified software investors, but Salesforce's early response looks encouraging.

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Disney Needs Its Next Hit Franchise. Can Pixar's Reluctant Leader Deliver?

The 'Toy Story' studio used to print money for Disney but hasn't made an original blockbuster in nearly a decade. Its top creative executive admits he's made mistakes.

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The Burger King President Who Took a Bite Out of McDonald's

Tom Curtis has gone viral by recording a video of himself chomping on a Whopper and even posting his phone number online.

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Western Alliance Sues Jefferies Over Soured Loan, Records Charge-Off

The regional bank says it will write off the loan as fears mount in the world of private credit.

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States Prepare Challenge to Major Broadcast TV Deal

A group of states plans to sue over Nexstar's $6.2 billion acquisition of Tegna combination if it gets FCC approval


(END) Dow Jones Newswires

March 09, 2026 05:15 ET (09:15 GMT)

Copyright (c) 2026 Dow Jones & Company, Inc.

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