Health Canada Approves Merck's Subcutaneous Version of Keytruda Cancer Drug

By Adriano Marchese


Canada's health regulator has approved Merck's new under-the-skin version of its cancer drug Keytruda, offering an alternative to the current intravenous infusion.

Health Canada has approved Keytruda SC, which is a new subcutaneous formulation of Merck's anti-PD-1 therapy called pembrolizumab.

The decision to approve the new version is based on results from pivotal trial 3475A-D77, it said, where the subcutaneous formulation was shown to deliver similar drug levels and effectiveness as the IV version when used with chemotherapy in certain lung-cancer patients.

The approval allows Merck to market the under-the-skin version of Keytruda in Canada, though the company said its rollout will depend on provincial and territorial reimbursement decisions.


Write to Adriano Marchese at adriano.marchese@wsj.com


(END) Dow Jones Newswires

February 17, 2026 11:38 ET (16:38 GMT)

Copyright (c) 2026 Dow Jones & Company, Inc.

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