Ionis Pharmaceuticals Inc

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Ionis Earnings: Peak Sales Raised for Olezarsen Ahead of Label Expansion; Positive Long-Term Outlook

Rachel Elfman

Apr 30, 2026

Ionis posted first‑quarter revenue of $246 million, up 86% year over year. Management raised its peak sales outlook for olezarsen to over $3 billion, from at least $2 billion as announced in January, and increased its 2026 revenue guidance by 9% at the midpoint.

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Ionis Pharmaceuticals Inc

Ionis Earnings: Peak Sales Raised for Olezarsen Ahead of Label Expansion; Positive Long-Term Outlook

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