Ionis Pharmaceuticals Inc

IONS: XNAS (USA)

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Ionis: Shares Soar on Positive Phase 3 Top-Line Results for Olezarsen in Severe Hypertriglyceridemia

Rachel Elfman

Sep 3, 2025

Ionis reported top-line data from the phase 3 study of olezarsen in severe hypertriglyceridemia. Compared with the placebo, olezarsen lowered triglycerides by up to 72% and resulted in an 85% reduction in acute pancreatitis events. Ionis' shares rose nearly 35% on Sept. 2.

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Ionis Pharmaceuticals Inc

Ionis: Shares Soar on Positive Phase 3 Top-Line Results for Olezarsen in Severe Hypertriglyceridemia

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