Intellia Therapeutics Inc

NTLA: XNAS (USA)

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Intellia: Shares Sink on Safety Concern in Phase 3 Trial; Lowering Fair Value to $60 From $75

Rachel Elfman

May 30, 2025

No-moat Intellia’s shares dropped 23% after the company disclosed one patient exhibited signs of severe liver stress in its ongoing nex-z phase 3 trial for transthyretin amyloidosis with cardiomyopathy, or ATTR-CM. Management stated that the patient’s elevated liver enzymes are resolving and have fallen to less dangerous levels. However, investors’ response underscores the heightened risk Intellia faces from clinical trial setbacks, given its lack of approved drugs and reliance on its pipeline candidates.

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Intellia Therapeutics Inc

Intellia: Shares Sink on Safety Concern in Phase 3 Trial; Lowering Fair Value to $60 From $75

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